BS and MS: University of Calcutta, India
PhD: NCBS-TIFR, India
Postdoctoral Research Associate: University of Pennsylvania
Research Assistant Professor: Syracuse University
We are interested to understand how the Central Nervous System (CNS = brain + spinal cord) forms and functions. The CNS is composed of many different types of neurons. Neurons are grouped in different types based on their functional characteristics, which include: the neurotransmitter they use (neurotransmitters are chemicals that neurons make and secrete to communicate with other neurons and non-neuronal cells), their location within the CNS and the connections they make within and outside the CNS. Every neuron connects to many other neurons and often to a variety of non-neuronal cells in a stereotyped yet complex manner. Establishing these connections is crucial for the proper execution of any behavior.
Using zebrafish, a simple vertebrate model organism, we aim to understand how different types of neurons form during early development and how they connect to each other and to their non-neuronal targets, for example, to body muscles required for locomotion. Deciphering the mechanisms behind these fundamental biological processes will not only strengthen our understanding of the formation and functions of the nervous system, but will also provide insights into how to repair nervous system damage following spinal cord injury or in diseases affecting the CNS.
Andrzejczuk LA *, Banerjee S *, England SJ, Voufo C, Kamara K and Lewis KE (2018) Tal1, Gata2a, and Gata3 Have Distinct Functions in the Development of V2b and Cerebrospinal Fluid-Contacting KA Spinal Neurons. Front. Neurosci. 12:170. doi: 10.3389/fnins.2018.00170
* These authors have contributed equally to this work.
England SJ, Campbell PC, Banerjee S, Swanson AJ, Lewis KE.
Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes. Front Cell Dev Biol. 2017 Feb 21;5:5. doi: 10.3389/fcell.2017.00005. eCollection 2017.
Banerjee S, Hayer K, Hogenesch JB, Granato M.
Zebrafish foxc1a drives appendage-specific neural circuit development.
Development. 2015 Feb 15;142(4):753-62. doi: 10.1242/dev.115816.
Banerjee S, Isaacman-Beck J, Schneider VA, Granato M.
A novel role for Lh3 dependent ECM modifications during neural crest cell migration in zebrafish.
PLoS One. 2013;8(1):e54609. doi: 10.1371/journal.pone.0054609. Epub 2013 Jan 18.
Banerjee S, Gordon L, Donn TM, Berti C, Moens CB, Burden SJ, Granato M.
A novel role for MuSK and non-canonical Wnt signaling during segmental neural crest cell migration.
Development. 2011 Aug;138(15):3287-96. doi: 10.1242/dev.067306.